Table 5 Diagnostic accuracy of GSDMD in the differential diagnosis of pleural effusion
From: Role of GSDMD and VEGF in differentiating between malignant and non-malignant pleural effusions
GSDMD | TPE versus TBPE | TPE versus MPE | TPE versus PIPE | MPE versus TBPE | MPE versus PIPE | TBPE versus PIPE |
|---|---|---|---|---|---|---|
AUC | 1.00 | 0.971 | 0.985 | 0.646 | 0.803 | 0.714 |
P value | 0.001* | 0.001* | 0.001* | 0.249 | 0.001* | 0.074 |
Cutoff point | ≥ 2.80 | ≥ 2.94 | ≥ 2.89 | ≥ 3.25 | ≥ 3.26 | ≥ 3.11 |
Sensitivity (%) | 100% | 96% | 91% | 83% | 87% | 75% |
Specificity (%) | 92% | 95% | 94% | 57% | 75% | 71% |
PPV (%) | 73% | 92% | 93% | 86% | 81% | 46% |
NPV (%) | 100% | 97% | 91% | 50% | 77% | 89% |
Accuracy (%) | 93% | 95% | 93% | 77% | 81% | 72% |