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Table 3 Age- and gender-adjusted multinomial logistic regression analysis of the association between interleukins (IL-22 and IL-33) and COVID-19

From: Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019

Cytokine; pg/mL

Group

Cases; n = 90

HC; n = 90

OR (95% CI)

p-value (pc)

n

%

n

%

IL-22

LP

5

5.6

45

50.0

Reference (1.0)

 < 0.001 (0.001)

HP

85

94.4

45

50.0

17.80 (6.48–48.90)

IL-33

LP

7

7.8

51

56.7

Reference (1.0)

 < 0.001 (0.001)

HP

83

92.2

39

43.3

19.0 (7.4–48.6)

 
  1. IL Interleukin, LP Low-production (≤ control median), HP High-production (> control median), HC Healthy controls, OR Odds ratio, CI Confidence interval, p: Two-tailed probability, pc: Bonferroni correction probability (significant p-value is indicated in bold)