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Table 2 The pathologic characteristics correlated with CD155 and CD56 proteins expression

From: Immunohistochemical expression of CD155 in invasive female breast carcinoma and its correlation with tumor infiltrating natural killer cells

Parameter

CD155

P value

CD56

P value

Positive [% within parameter]

Negative [% within parameter]

 

High [% within parameter]

Low [% within parameter]

Histological Type

      

IDC-NST

20 [30.8]

45 [69.2]

0.362

19 [29.2]

46 [70.8]

0.402

ILC

1 [14.3]

6 [85.7]

 

1 [14.3]

6 [85.7]

 

Histological grade

      

Low

12 [25]

36 [75]

0.163

8 [16.7]

40 [83.3]

0.004

High

12 [40]

18 [60]

 

14 [46.7]

16 [53.3]

 

T Stage

      

Early (T1 + T2)

20 [29.4]

48 [70.6]

0.498

18 [26.5]

50 [73.5]

0.375

Advanced (T3 + T4)

4 [40]

6 [60]

 

4 [40]

6 [60]

 

Lymph node metastasis

      

Negative

8 [22.2]

28 [77.8]

0.13

11 [30.6]

25 [69.4]

0.669

Positive

16 [38.1]

26 [61.9]

 

11 [26.2]

31 [73.8]

 

Anatomic Stage

      

Early [I and II]

16 [27.6]

42 [72.4]

0.3

17 [29.3]

41 [70.7]

0.712

Advanced [III and IV]

8 [40]

12 [60]

 

5 [25]

15 [75]

 

Prognostic stage

      

Early [I and II]

8 [19.5]

33 [80.5]

0.003

10 [24.4]

31 [75.6]

0.187

Advanced [III and IV]

15 [53.6]

13 [46.4]

 

11 [39.3]

17 [60.7]

 

ER

      

Positive

16 [24.2]

50 [75.8]

0.003

16 [24.2]

50 [75.8]

0.068

Negative

8 [66.7]

4 [33.3]

 

6 [50]

6 [50]

 

PR

      

Positive

11 [19.3]

46 [80.7]

0.000

11 [19.3]

46 [80.7]

0.004

Negative

13 [61.9]

8 [38.1]

 

11 [52.4]

10 [47.6]

 

HER2

      

Positive

5 [35.7]

9 [64.3]

0.658

7 [50]

7 [50]

0.045

Negative

19 [29.7]

45 [70.3]

 

15 [23.4]

49 [76.6]

 

Ki-67 index

      

Low

6 [18.2]

27 [81.8]

0.039

4 [12.1]

29 [87.9]

0.007

High

18 [40]

27 [60]

 

18 [40]

27 [60]

 

BC Subtypes

      

Luminal A Like

2 [9.1]

20 [90.9]

0.01

0 [0]

22 [100]

0.007

Luminal B like-HER2 negative

12 [35.3]

22 [64.7]

 

11 [32.4]

23 [67.6]

 

Luminal B like-HER2 positive

2 [20]

8 [80]

 

5 [50]

5 [50]

 

HER2 positive-non luminal

3 [75]

1 [25]

 

2 [50]

2 [50]

 

Triple negative

5 [62.5]

3 [37.5]

 

4 [50]

4 [50]

 

LVI

      

Positive

12 [31.6]

26 [68.4]

0.88

10 [26.3]

28 [73.7]

0.718

Negative

12 [30]

28 [70]

 

12 [30]

28 [70]

 

Stromal TILs

      

Low

15 [25.4]

44 [74.6]

0.071

10 [16.9]

49 [83.1]

0.000

High

9 [47.4]

10 [52.6]

 

12 [63.2]

7 [36.8]

 
  1. Bold values indicate the strong significant correlation