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Table 2 Comparison of NIHSS and mean serum levels of TAC, TOS, MDA, catalase, paraoxonase and neopterin, in the drug group before and after the intervention

From: Investigation of the effect of N-acetylcysteine on serum levels of oxidative inflammatory biomarkers in patients with stroke

Tests and parameters

Control (before) Mean ± SD

Control (after) Mean ± SD

P value (Before-afterControl)

Intervention (before) Mean ± SD

Intervention (after) Mean ± SD

P value (Before-after Intervention)

TAC

3227.79 ± 192.53

3281 ± 279.37

0.82

3474 ± 257.48

3579.50 ± 210.16

0.75

TOS

74 ± 9.10

71.49 ± 8

0.83

113.28 ± 12.57

79.70 ± 8.25

0.02

MDA

11.84 ± 1.26

11.49 ± 6.23

0.78

10.14 ± 1.75

8.30 ± 1.24

0.42

catalase

4.87 ± 1.22

7.60 ± 1.38

0.14

4.44 ± 0.68

6.19 ± 0.94

0.10

paraoxonase

21.97 ± 1.61

20.75 ± 1.38

0.55

22.03 ± 1.43

22.61 ± 1.35

0.55

neopterin

2.02 ± 0.56

0.97 ± 0.14

0.06

1.81 ± 0.36

1.54 ± 0.27

0.13

NIHSS

Control

P value

Intervention

P value

NIHSS at the first visit

8.64 ± 1.1.19

0.14*

6.55 ± 1

–

NIHSS After 24 h

6.82 ± 1.24

0.134*

4.38 ± 0.99

 < 0.001**

NIHSS After 2 weeks

5.93 ± 1.36

0.050*

2.94 ± 0.70

 < 0.001**

NIHSS After 1 month

6 ± 1.63

0.02*

2.22 ± 0.56

0.001**

NIHSS After 3 months

3.53 ± .71

0.057*

1.83 ± 0.51

0.001**

  1. **Calculated for each NIHSS after a certain period post-intervention when compared to NIHSS reported at the first visit (6.55 ± 1) in intervention group
  2. *Calculated for each NIHSS after a certain period post-intervention when compared to NIHSS evaluated in corresponding control group