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Table 3 Comparison of mean serum levels of TAC, TOS, MDA, paraoxonase, catalase, and neopterin between intervention-responsive and non-responsive subgroups before and after the intervention

From: Investigation of the effect of N-acetylcysteine on serum levels of oxidative inflammatory biomarkers in patients with stroke

Variables

After intervention

Before intervention

P value

Mean ± SD

Mean ± SD

Intervention-non-responsive group

Intervention-non-responsive group

TAC

2791.15 ± 760.04 (n = 20)

3606 ± 1003.20 (n = 20)

 < 0.001

TOS

102.04 ± 23.40 (n = 15)

65.54 ± 22.25 (n = 15)

 < 0.001

MDA

13.60 ± 6.51 (n = 11)

8.45 ± 3.48 (n = 11)

0.002

paraoxonase

20.50 ± 4.71 (n = 13)

26.19 ± 4.77 (n = 13)

 < 0.001

catalase

3.61 ± 2.81 (n = 14)

6.53 ± 5.38 (n = 14)

0.03

neopterin

1.74 ± 0.73 (n = 10)

1.07 ± 0.77 (n = 10)

0.001

Variables

Intervention-responsive group

Intervention-responsive group

–

TAC

4208.1 ± 767.15 (n = 17)

3072.5 ± 938.61 (n = 17)

 < 0.001

TOS

58.13 ± 30.46 (n = 22)

115.55 ± 56.69 (n = 22)

 < 0.001

MDA

8.18 ± 4.58 (n = 26)

11.89 ± 6.75 (n = 26)

 < 0.001

Paraoxonase

22.68 ± 6.34 (n = 24)

19.73 ± 6.14 (n = 24)

 < 0.001

Catalase

8.80 ± 4.97 (n = 23)

3.42 ± 2.44 (n = 23)

 < 0.001

Neopterin

1.11 ± 1.05 (n = 27)

2.21 ± 2.17 (n = 27)

0.001