Bioactivity assays and phytochemical analysis upon Achillea filipendulina, focusing on xanthine oxidase inhibitory and antimalarial properties

Asnaashari, Solmaz; Marefat, Sahar; Vatankhah, Amir Mansour; Bamdad Moghaddam, Sedigheh; Delazar, Abbas; Hamedeyazdan, Sanaz

doi:10.1186/s43088-023-00385-6

Beni-Suef University Journal of Basic and Applied Sciences

Table 1 Components of the essential oil of A. filipendulina

From: Bioactivity assays and phytochemical analysis upon Achillea filipendulina, focusing on xanthine oxidase inhibitory and antimalarial properties

No.	Compounds	Retention time	Percentage	Mw*	Formula	KI**
1	2,5,5 Trimethyl-3,6-heptadien-2-ol	15.93	0.5	154	C₁₀H₁₈O	876
2	Para cymene	16.62	0.6	134	C₁₀H₁₄	968
3	Eucalyptol	17.05	7.5	154	C₁₀H₁₈O	1006
4	Santolina alcohol	17.37	17.9	154	C₁₀H₁₈O	1018
5	Butyric acid	17.9	0.6	170	C₁₀H₁₈O₂	1039
6	Gamma-terpinene	18.01	0.3	136	C₁₀H₁₆	1043
7	Butanoic acid	18.22	1.4	170	C₁₀H₁₈O₂	1051
8	Artemisia alcohol	18.68	0.7	154	C₁₀H₁₈O	1068
9	Alpha-campholene aldehyde	19.92	0.6	154	C₁₀H₁₆O	1113
10	Alpha-campholenic aldehyde	20.03	0.6	154	C₁₀H₁₈O	1116
11	Camphor	20.54	1.6	152	C₁₀H₁₆O	1131
12	Pinocarveol	20.62	1.5	152	C₁₀H₁₆O	1135
13	Pinocarvone	21.11	1.4	150	C₁₀H₁₄O	1149
14	Isoborneol	21.51	4.8	154	C₁₀H₁₈O	1161
15	Borneol	21.69	5.5	154	C₁₀H₁₈O	1166
16	Terpinen-4-ol	21.94	2.5	154	C₁₀H₁₈O	1174
17	α-Terpinyl propionate	22.22	1.3	154	C₁₀H₁₈O	1183
18	Alpha-terpineol	22.45	0.6	152	C₁₀H₁₆O	1189
19	Piperitol	22.77	0.2	152	C₁₀H₁₈O	1199
20	Carveol	23.04	0.4	152	C₁₀H₁₆O	1208
21	Nerol	23.36	0.9	154	C₁₀H₁₈O	1218
22	Isobornyl formate	23.45	1.3	182	C₁₁H₁₈O₂	1221
23	Alpha-terpinyl acetate	23.63	2.4	182	C₁₂H₂₀O₂	1227
24	Ascaridole	24.03	0.3	168	C₁₀H₁₆O₂	1240
25	Chrysanthenyl acetate	24.47	3.6	192	C₁₂H₁₆O₂	1255
26	Isobornyl acetate	25.28	4.3	196	C₁₂H₂₀O₂	1281
27	Isoascaridole	25.51	0.3	168	C₁₀H₁₆O₂	1288
28	Eugenol	26.93	0.2	164	C₁₀H₁₂O₂	1336
29	Methoxyallylbenzene	27.24	1.9	196	C12H20O2	1347
30	β-Elemene	28.69	0.2	204	C₁₅H₂₄	1398
31	Trans-β-Caryophyllene	29.65	0.4	204	C₁₅H₂₄	1432
32	Germacrene	31.28	2.9	204	C₁₅H₂₄	1492
33	Geranyl isovalerate	33.3	1.73	238	C₁₅H₂₆O₂	1570
34	Spathulenol	33.68	2.8	220	C₁₅H₂₄O	1585
35	Mint ketone	33.99	0.4	999	C₁₅H₂₄O	1597
36	Torreyol	35.03	2.7	222	C₁₅H₂₆O	1640
37	Tridecanal	36.5	0.3	198	C₁₃H₂₆O	1707
38	Alloaromadendrene	37.37	0.9	204	C₁₅H₂₄	1739
39	γ-costol	37.51	0.4	220	C₁₅H₂₄O	1744
40	Hexahydrofarnesyl acetone	39.57	0.3	268	C₁₈H₃₆O	1836
41	Palmitic acid	41.93	0.2	254	C₁₆H₃₂O₂	1946
Total		78.93
Monoterpene hydrocarbons		59.3
Oxygenated Monoterpenes		3.9
Sesquiterpenes		10.6
Non-terpenoids		3.73
Unidentified		1.4

M_W*: Molecular weight
KI**: Kovats retention Index

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