Table 1 Main critical factors affecting the manufacturing a 3D printing product
Methods | Range of material | Process critical factors | Material critical factors | References |
|---|---|---|---|---|
Extrusion based printing | Liquid, past, gel, slurry | Nozzle orifice diameter, extrusion temperature, cooling rate extrusion pressure, speed of traveling printing profile, feeding rate, fill percentage Line spacing. | Type of polymer, molecular weight, viscosity, glass transition temperature, strength, toughness, type of plasticizer and its concentration, polymer to drug ratio, Filament diameter. Kind of solvent to load drug into filament. | |
Powder bed technique | Powder, liquid binder | Printer head shape, number, speed, and its movement pattern layer thickness Powder bed spreading speed, powder bed temperature Speed of drying of powder bed between layers Temperature of heater in post printing step. | Powder particle size, shape and density , moisture content. Binder concentration, viscosity, surface tension, thermal capacity, electrical Conductivity, droplet volume. | |
Material jetting | Liquid | Droplet flight path Surface wetting Jetting heating system and its temperature. | Droplet cauterization like size concentration/viscosity/ionic strength and stability, Kind of solvent. |