Articles

Preparation and characterization of polymyxin B- and histidine-coupled magnetic nanoparticles for purification of biologics from acquired endotoxin contamination

Endotoxin is a major process-related impurity that can act as a strong immunostimulant leading to fever and hypotensive shock. Thus, the US FDA and international quality standards strictly direct the biologics...

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In situ green analytical methods for the rapid and sensitive determination of a newly launched orphan anticancer drug; Tigecycline in infusion bags: comparative study

Tigecycline (TIG), an antimicrobial agent indicated for complex bacterial infections, is now approved by FDA as an orphan chemotherapeutic agent for the treatment of acute myeloid leukemia due to its inhibitor...

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The study of Piszkiewicz’s and Berezin’s models on the redox reaction of allylthiourea and bis-(2-pyridinealdoximato)dioxomolybdate(IV) complex in an aqueous acidic medium

The study of Piszkiewicz’s and Berezin’s models on the redox reaction of allylthiourea and bis-(2-pyridinealdoximato)dioxomolybdate(IV) complex ([Mo^IVO₂(paoH)₂]²⁻) in an aqueous acidic medium is suggested. The Pi...

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An endpoint visualization loop-mediated isothermal amplification (LAMP) for detecting bubaline theileriosis

Tropical theileriosis is a significant disease affecting the health and production levels of buffaloes in India. It is caused by an apicomplexan—Theileria annulata. The timely and accurate detection of infection ...

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Synthesis, characterization and antibiotic evaluation of some novel (E)-3-(4-diphenylamino)phenyl)-1-(4′-fluorophenyl)prop-2-en-1-one chalcones and their analogues

The increase in resistance of pathogenic organisms to the available chemotherapeutic agents are critical challenges in drug design and development, motivating researchers to look for novel compounds that can c...

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Analysis of codon usage patterns in open reading frame 4 of hepatitis E viruses

Hepatitis E virus (HEV) is a member of the family Hepeviridae and causes acute HEV infections resulting in thousands of deaths worldwide. The zoonotic nature of HEV in addition to its tendency from human to human...

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Coinfection of fungi with SARS-CoV-2 is a detrimental health risk for COVID-19 patients

Notable fungal coinfections with SARS-CoV-2 in COVID-19 patients have been reported worldwide in an alarming way. Mucor spp. and Rhizopus spp. were commonly known as black fungi, whereas Aspergillus spp. and Cand...

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Sepia officinalis ink mitigates gastric ulcer via modulation of antioxidant/anti-inflammatory pathways

Sepia officinalis ink is a bioactive secondary metabolite rich in melanin granules, which has a wide range of nutritional and therapeutic values and also has been used to prevent various gastrointestinal disorder...

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Diagnostic accuracy, available treatment, and diagnostic methods of dental caries in practice: a meta-analysis

Diagnosis of dental caries and identification of patients with dental caries is the biggest challenge in dentistry. For this diagnostic accuracy, several methods are studied. The present study attempts to re-s...

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Quaternionic quantum mechanics for N = 1, 2, 4 supersymmetry

Quaternions have emerged as powerful tools in higher-dimensional quantum mechanics as they provide homogeneous four-dimensional structure in quantum field theories, offer compact representations, and incorpora...

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Maternal supplementation of α-lipoic acid attenuates prenatal cytarabine exposure-induced oxidative stress, steroidogenesis suppression and testicular damage in F1 male rat fetus

Cytarabine (Ara-C) is an anticancer drug, which is considered as the mainstay in the treatment of hematological malignancies, known to cause various teratogenic effects. Alpha-lipoic acid (ALA) is a natural an...

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Synthesis and characterization of poly (styrene-co-acrylamide)-graft-polyanilines as new sorbents for mercuric present in aqueous hydrocarbon liquids

The unprocessing hydrocarbon oil often contains high concentrations of mercury, which damages the metallic processing components and have health risk on workers and environment. Mercuric removal unit associate...

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Cytotoxic effects of chitosan nanoparticles containing Zataria multiflora essential oil against human breast and melanoma cells

Breast cancer is the most common cancer among women, and melanoma incidence increases worldwide. The emergence of drug resistance and side effects of chemotherapy drugs has led to a great deal of attention bei...

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Effect of pressures and type of ventilation on aerosol delivery to chronic obstructive pulmonary disease patients

Continuous Positive Airway Pressure (CPAP), BiPhasic Positive Airway Pressure (BiPAP), and high flow nasal cannula (HFNC) show some evidence to have efficacy in COVID-19 patients. Delivery during noninvasive m...

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Comparison of the antibacterial properties of phycocyanin and its SNPs and their effects on rat blood cells and liver enzymes

Phycocyanin is an important protein in cyanobacteria that has many medical and therapeutic properties. The aim of the present study was to compare the antibacterial properties of phycocyanin and its SNPs and t...

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Pentacam versus anterior segment OCT in measuring intended versus achieved ablation depth post-myopic LASIK correction

Accurate quantitative measurements of central corneal thickness (CCT) provide valuable, clinical information for preoperative assessment, surgical planning, and follow-up in myopic patients who have undergone ...

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Clinicophysiological and hematobiochemical effect of dexmedetomidine or diazepam with ketamine and propofol in total intravenous anesthesia in goats

Total intravenous anesthesia (TIVA) is a well-documented anesthetic concept for some animal species, including dogs and horses; however, information about TIVA protocols in goats is currently inadequate. There...

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Computational and pharmacokinetics studies of 1,3-dimethylbenzimidazolinone analogues of new proposed agent against Alzheimer's disease

Alzheimer's disease (AD) is a multifactorial disorder that gradually destroys wisdom and memory skills. Currently, this disease can only be treated palliatively. However, the molecular mechanisms underlying th...

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Investigation of rectangular apertures and their application on speckle imaging

An aperture in the form of four squares arranged symmetrically along the cartesian coordinates with equal distances from the center investigated. Three models are suggested in the computation of the Point Spre...

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Bacteriocins from lactic acid bacteria: purification strategies and applications in food and medical industries: a review

Bacteriocins are generally defined as ribosomally synthesized peptides, which are produced by lactic acid bacteria (LAB) that affect the growth of related or unrelated microorganisms. Conventionally, the extra...

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Kinetics and thermodynamics of Cr (VI) reduction by Tamarindus indica methanol leaves extract under optimized reaction conditions

Environmental contamination with Cr (VI) has recently attracted public attention because of its high concentration in soil and wastewater originating majorly from anthropogenic activities and natural processes...

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Therapeutic applications of engineered chimeric antigen receptors-T cell for cancer therapy

Findings of new targeted treatments with adequate safety evaluations are essential for better cancer cures and mortality rates. Immunotherapy holds promise for patients with relapsed disease, with the ability ...

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Assessment of Verbesina alternifolia and Mentha piperita oil extracts on Clinostomum phalacrocoracis metacercariae from Tilapia zillii

Clinostomiasis (yellow grub disease) is a disease of freshwater fish caused by the encysted metacercariae (EMC) of Clinostomum spp. showing retarded growth, unusual host behavior, and even death in fishes. Thus, ...

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Prospective Asian plants with corroborated antiviral potentials: Position standing in recent years

Viral diseases are extremely widespread infections caused by viruses. Amongst numerous other illnesses, viral infections have challenged human existence severely. Over the history of mankind, new viruses have ...

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Encapsulation of probiotics: past, present and future

Probiotics are live microbial supplements known for its health benefits. Consumption of probiotics reported to improve several health benefits including intestinal flora composition, resistance against pathogens....

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Costus root extract improves testicular toxicity of Bisphenol A in adult male albino rats: histopathological, ultrastructural and biochemical studies

Bisphenol A (BPA) causes environmental pollution and is used as a natural antioxidant to protect against chemical side-effects. Costus is a well-known medicinal plant containing several biologically active com...

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Correspondence on “piperine as a potential molecule for disease prevention and management

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Phyto-factories of anti-cancer compounds: a tissue culture perspective

Cancer is one of the most critical but ubiquitous causes of death grappled from past decades. Widely used chemotherapy with cytotoxic activity blocks/ kills the cancer cell. The compounds targeted for anticanc...

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Rydberg energies and transition probabilities of Li I for np–ms (m ≤ 5) transitions

Mathematical modeling provides grounds for understanding scientific systems theoretically. It serves as a guide for experimentalists in determining directions of investigation. Recently, the Covid-19 pandemic ...

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The role of protein phosphatase 2A tau axis in traumatic brain injury therapy

Traumatic brain injury (TBI) is a debilitating disorder due to trauma caused by an external mechanical force eventually leading to disruption in the normal function of the brain, with possible outcomes includi...

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Prediction of the hot asphalt mix properties using deep neural networks

Marshall design process is the most common method used for estimating the Optimum asphalt content (OAC) and this process is called the asphalt mix design. However, this method is time-consuming, labor-intensiv...

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Investigation of a new modulated aperture using speckle techniques

A design of equally spaced eight-circles placed at equal distances from the origin is suggested. Three models corresponding to the eight-circle design considering conic, linear, and quadratic distributions are...

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Identification and mapping of QTL associated with some traits related for drought tolerance in wheat using SSR markers

Wheat is the most important crop around the world. Drought stresses affect wheat production and their characterization. Most of the traits that are affected by drought are quantitative traits, so detection of ...

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Tailoring enhanced production and identification of isoflavones in the callus cultures of Pueraria thomsonii Benth and its model verification using response surface methodology (RSM): a combined in vitro and statistical optimization

Scientifically, isoflavones from Pueraria thomsonii Benth possess diverse pharmacological activities and have been used to treat various diseases. In vitro propagation of callus has contributed to the reliability...

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Dynamic on-bottom stability analysis of subsea pipelines using finite element model-based general offshore analysis software: a case study

The dynamic on-bottom stability analysis represents a fundamental task in the design process of the subsea pipelines. Such analysis ensures the stability of the as-laid pipeline on the seabed against the later...

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Various vaccine platforms in the field of COVID-19

With the emergence of Corona virus Disease-2019, a novel worldwide health disaster is threatening the population. The WHO declared COVID-19 as a pandemic in December 2019, when it first surfaced in Hunan seafo...

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Intelligent system based comparative analysis study of SARS-CoV-2 spike protein and antigenic proteins in different types of vaccines

Coronaviruses, members of the Coronavirinae subfamily in the Coronaviridae family, are enveloped and positive-stranded RNA viruses that infect animals and humans, causing intestinal and respiratory infections....

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Functional food: complementary to fight against COVID-19

The novel coronavirus has embarked on a global pandemic and severe mortality with limited access for its treatments and medications. For the lack of time, research, and enough efficacy, most vaccines are under...

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Molecular docking prediction and in vitro studies elucidate anti-inflammatory effect of Garcinia extract against inducible nitric oxide synthase and cyclooxygenase-2 targets

Garcinia is a tropical plant that has been traditionally used in medicinal folklore for its potential antioxidant, antibacterial, anti-hyperlipidemic, anti-diabetic, hepatoprotective, etc. In this study, methanol...

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A retrospective study of electrodiagnostically evaluated ulnar neuropathies with special guidelines for ulnar neuropathies at elbow

The diagnosis of type, severity of ulnar neuropathy based on symptoms and clinical tests are unsatisfactory. This study aimed to retrospectively analyze ulnar neuropathies at different sites evaluated through ...

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Gene polymorphisms of Interleukin 6 (−174 G/C) and transforming growth factor β-1(+915 G/C) in ovarian cancer patients

In the study on hand, we investigated the effect of IL-6 (−174 G/C; rs 1800795) and TGF-β1 (+915G/C; rs 1800471) gene polymorphisms on the susceptibility to Ovarian Cancer and their effect on plasma levels. IL...

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Assessment of twist tape thermal performance in heat transfer passive augmentation technique

Processing processes such as petrochemical, refineries, pharmaceutical, thermal, chemical, and integrated chemical industries such as the food, dairy and sugar industries have been widely used for heat exchang...

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Role of ultrasound and Doppler findings as a predictor of thyroid hormonal levels in cases of Hashimoto thyroiditis

Chronic lymphocytic thyroiditis or Hashimoto’s thyroiditis (HT) is a common form of organ specific autoimmune disease mediated by anti-thyroid autoantibodies. Ultrasound including Doppler is helpful diagnostic...

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Phytochemical screening, antioxidant study and hematinic property of Mojeaga herbal remedy using animal model

Plants have been used as medicine since ancient time and contributed immensely to health care delivery system globally. The aim of this study was to evaluate the phytoconstituents, antioxidant and hematinic pr...

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Foliar application of nutrients on medicinal and aromatic plants, the sustainable approaches for higher and better production

The most important advantages of foliar fertilization are to improve plant growth and crop quality, appropriately manage the nutritional status of plants, enhance disease resistance and regulate nutrient defic...

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A hyper-resolving polynomial aperture and its application in microscopy

A hyper-resolving aperture composed of a polynomial distribution is suggested. The point spread function (PSF) is computed and compared with that corresponding to linear, quadratic, and circular apertures. In ...

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Improving the accuracy of tumor surgery by THz imaging and making the results of pathological anatomy faster by THz spectroscopy

The terahertz radiation is a specific part of the electromagnetic radiation spectrum and has multiple significant applications in multiple scientific researches such as the applications in the medicine. An imp...

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Molecular basis of AR and STK11 genes associated pathogenesis via AMPK pathway and adipocytokine signalling pathway in the development of metabolic disorders in PCOS women

One of the most common hormonal disorders in women of reproductive age is polycystic ovary syndrome (PCOS). In recent years, it has been found that insulin resistance is a common metabolic abnormality in women...

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Resistance training is an effective exercise therapy in cardiac rehabilitation program for patients with coronary artery disease: a systematic review

Exercise-based cardiac rehabilitation program is a comprehensive intervention for the rehabilitation of coronary artery disease patients. Exercise therapy is a valuable, effective, and integral intervention of...

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Morphological and molecular identification of Sarcocystis sp. from the little grebe, Tachybaptus ruficollis (Aves: Podicipediformes), for the first time in Egypt

In Egypt, studies of sarcocystosis in migratory and wading birds specially Podicipediformes are scarce. Therefore, the occurrence of Sarcocystis spp. in the little grebe, Tachybaptus ruficollis (Podicipediformes:...

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