Skip to main content

Table 1 2-Anilimopyrimidine derivatives with their activities

From: In silico studies of some 2-anilinopyrimidine derivatives as anti-triple-negative breast cancer agents

CompoundsRXExperimental activities (IC50)Calculated activities (pIC50)
1HO55.24.26
2O84.54.07
3S57.44.24
4CH286.84.06
5O73.44.13
6S65.04.19
7CH278.14.11
8O80.74.09
9S56.54.25
10CH271.74.14
11HO71.84.14
12HCH245.14.35
13MeO51.34.29
14MeS61.34.21
15ClCH221.34.67
16ClO61.64.21
17ClS62.74.20
18ClCH252.14.28
19O77.14.11
20S78.34.11
21CH253.14.24
22O69.74.16
23S36.04.44
24CH253.14.27
2588.04.06
2688.04.06
2764.64.19
2869.74.16
2962.04.21
3016.94.77