Table 6 ADME and drug-likeness properties
S/N | WLOGP | TPSA | GI absorption | BBB permeant | Pgp substrate | Bioavailability score | Lipinski violations | Synthetic accessibility |
|---|---|---|---|---|---|---|---|---|
3 | 4.76 | 65.5 | High | Yes | No | 0.55 | 0 | 3.05 |
4 | 3.6 | 65.5 | High | Yes | No | 0.55 | 0 | 3.13 |
5 | 3.55 | 74.73 | High | Yes | Yes | 0.55 | 0 | 3.18 |
6 | 4.51 | 65.5 | High | Yes | No | 0.55 | 0 | 3.07 |
8 | 3.85 | 65.5 | High | Yes | Yes | 0.55 | 0 | 3.04 |