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Table 5 Statistical parameters of built models

From: QSAR, QSTR, and molecular docking studies of the anti-proliferative activity of phenylpiperazine derivatives against DU145 prostate cancer cell lines

Parameter

Model 1

Model 2

Model 3

Model 4

Friedman LOF

0.081427

0.161877

0.176692

0.178387

R-squared

0.865187

0.731993

0.707465

0.704658

Adjusted R-squared

0.831483

0.664991

0.634331

0.630823

Cross validated R-squared

0.778806

0.550227

0.438354

0.483458

Significant regression

Yes

Yes

Yes

Yes

Significance-of-regression F-value

25.67064

10.92497

9.673568

9.543635

Critical SOR F-value (95%)

3.055818

3.055818

3.055818

3.055818

Replicate points

0

0

0

0

Computed experimental error

0

0

0

0

Lack-of-fit points

16

16

16

16

Min expt. error for non-significant LOF (95%)

0.104609

0.147494

0.154096

0.154833