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Table 2 Effect of test compounds on egg albumin protein denaturation

From: Synthesis, characterization, and investigation of the anti-inflammatory effect of 2,3-disubstituted quinazoline-4(1H)-one

Design of treatment

Concentration (μg/ml)

Mean ± SEM

% inhibition

Group-I (control)

–

1.2 ± 0.059

–

Group-II (diclo)

50

0.55 ± 0.015*

54.16

100

0.49 ± 0.040**

59.16

150

0.42 ± 0.033**

65.00

200

0.40 ± 0.080**

66.66

250

0.36 ± 0.032**

70.00

Group-III (G1)

50

0.78 ± 0.047

35.00

100

0.78 ± 0.048*

35.00

150

0.78 ± 0.047*

35.00

200

0.72 ± 0.006**

40.00

250

0.71 ± 0.002**

40.00

Group-IV (G2)

50

0.71 ± 0.002

40.83

100

0.71 ± 0.008

40.83

150

0.71 ± 0.009*

40.83

200

0.70 ± 0.008*

41.66

250

0.70 ± 0.006**

41.66

Group-V (G3)

50

0.82 ± 0.014

31.66

100

0.80 ± 0.011*

33.33

150

0.75 ± 0.003*

37.50

200

0.73 ± 0.009**

39.00

250

0.61 ± 0.004**

49.16

  1. Values are expressed as mean ± SEM (n = 6) and ANOVA followed by Dunnett’s test
  2. *p < 0.05, **p < 0.001 when compared with control