Skip to main content

Table 6 Anti-hypertensive activity of various Rauvolfia species

From: Identification of suitable substitute for Sarpagandha (Rauvolfia serpentina (L.) Benth. ex Kurz) by phytochemical and pharmacological evaluation

Groups

Before induced with DOCA salt

After induced with DOCA salt

After treatment with plant extract

Diastolic

Systolic

Diastolic

Systolic

Diastolic

Systolic

Group I

57 ± 1

110 ± 1

62 ± 1

114 ± 1

65 ± 1

110 ± 1

Group II

61 ± 2#

112 ± 1#

113 ± 1.52#

177 ± 1#

130 ± 1.52#

207 ± 1#

Group III (enalapril)

70 ± 1

117 ± 1

106 ± 1

167 ± 1

68 ± 1*

126 ± 1.52*

Group IV (RSR)

63 ± 0.7

123 ± 0.3

93 ± 0.7*

163 ± 0.3*

81 ± 0.4*

157 ± 0.9

Group V (RHR)

67 ± 1

112 ± 2

101 ± 1

151 ± 2

78 ± 1

107 ± 1

Group VI (RMR)

59 ± 2

113 ± 0.7

102 ± 0.2

173 ± 0.7

97 ± 0.3

151 ± 0.23

Group VII (RTR)

66 ± 1

115 ± 1.5

103 ± 1*

161 ± 1.5*

92 ± 1*

121 ± 1*

Group VIII (RVR)

65 ± 1

110 ± 1

97 ± 1

160 ± 1

89 ± 0.3*

112 ± 0.43*

  1. Values are mean ± SD, n = 6
  2. #p < 0.05 when compared to GPI normal
  3. *p < 0.05 when compared to GP-II control by ANOVA followed by Dunnett’s post-test