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Table 6 Anti-hypertensive activity of various Rauvolfia species

From: Identification of suitable substitute for Sarpagandha (Rauvolfia serpentina (L.) Benth. ex Kurz) by phytochemical and pharmacological evaluation

Groups Before induced with DOCA salt After induced with DOCA salt After treatment with plant extract
Diastolic Systolic Diastolic Systolic Diastolic Systolic
Group I 57 ± 1 110 ± 1 62 ± 1 114 ± 1 65 ± 1 110 ± 1
Group II 61 ± 2# 112 ± 1# 113 ± 1.52# 177 ± 1# 130 ± 1.52# 207 ± 1#
Group III (enalapril) 70 ± 1 117 ± 1 106 ± 1 167 ± 1 68 ± 1* 126 ± 1.52*
Group IV (RSR) 63 ± 0.7 123 ± 0.3 93 ± 0.7* 163 ± 0.3* 81 ± 0.4* 157 ± 0.9
Group V (RHR) 67 ± 1 112 ± 2 101 ± 1 151 ± 2 78 ± 1 107 ± 1
Group VI (RMR) 59 ± 2 113 ± 0.7 102 ± 0.2 173 ± 0.7 97 ± 0.3 151 ± 0.23
Group VII (RTR) 66 ± 1 115 ± 1.5 103 ± 1* 161 ± 1.5* 92 ± 1* 121 ± 1*
Group VIII (RVR) 65 ± 1 110 ± 1 97 ± 1 160 ± 1 89 ± 0.3* 112 ± 0.43*
  1. Values are mean ± SD, n = 6
  2. #p < 0.05 when compared to GPI normal
  3. *p < 0.05 when compared to GP-II control by ANOVA followed by Dunnett’s post-test