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Table 8 Analgesic activity of various Rauvolfia species by hot plate method

From: Identification of suitable substitute for Sarpagandha (Rauvolfia serpentina (L.) Benth. ex Kurz) by phytochemical and pharmacological evaluation

 

Reaction time in seconds at time (min)

0 min

60 min

90 min

120 min

GP I (control)

1.17 ± 0.05

1.22 ± 0.12#

1.28 ± 0.16#

1.38 ± 0.19#

GP II (standard)

1.46 ± 0.09

7.18 ± 0.31

6.62 ± 0.35

6.57 ± 0.62

GP III (RHR)

1.20 ± 0.07

5.61 ± 0.36

5.77 ± 0.34

5.38 ± 0.30

GP IV (RTR)

1.25 ± 0.08

5.38 ± 0.50

5.56 ± 0.42

5.35 ± 0.29

GP V (RSR)

1.29 ± 0.08

4.78 ± 0.32

4.88 ± 0.53*

4.64 ± 0.42*

GP VI (RMR)

1.30 ± 0.06

6.91 ± 0.32

6.88 ± 0.30

6.70 ± 0.34

GPVII (RVR)

1.45 ± 0.08

6.33 ± 0.33

6.28 ± 0.32

5.99 ± 0.40*

  1. Values are mean ± SD, n = 6
  2. #p < 0.05 when compared to GPI normal
  3. *p < 0.05 when compared to GP-II control by ANOVA followed by Dunnett’s post-test