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Table 8 Analgesic activity of various Rauvolfia species by hot plate method

From: Identification of suitable substitute for Sarpagandha (Rauvolfia serpentina (L.) Benth. ex Kurz) by phytochemical and pharmacological evaluation

  Reaction time in seconds at time (min)
0 min 60 min 90 min 120 min
GP I (control) 1.17 ± 0.05 1.22 ± 0.12# 1.28 ± 0.16# 1.38 ± 0.19#
GP II (standard) 1.46 ± 0.09 7.18 ± 0.31 6.62 ± 0.35 6.57 ± 0.62
GP III (RHR) 1.20 ± 0.07 5.61 ± 0.36 5.77 ± 0.34 5.38 ± 0.30
GP IV (RTR) 1.25 ± 0.08 5.38 ± 0.50 5.56 ± 0.42 5.35 ± 0.29
GP V (RSR) 1.29 ± 0.08 4.78 ± 0.32 4.88 ± 0.53* 4.64 ± 0.42*
GP VI (RMR) 1.30 ± 0.06 6.91 ± 0.32 6.88 ± 0.30 6.70 ± 0.34
GPVII (RVR) 1.45 ± 0.08 6.33 ± 0.33 6.28 ± 0.32 5.99 ± 0.40*
  1. Values are mean ± SD, n = 6
  2. #p < 0.05 when compared to GPI normal
  3. *p < 0.05 when compared to GP-II control by ANOVA followed by Dunnett’s post-test