Table 2 Characteristics of individual studies for the associations between ER polymorphisms and the risk of OAG
From: The association of estrogen-signaling pathways and susceptibility to open-angle glaucoma
Author | Country | Polymorphism | Type | Gender (f/m)a | Ageb | Genotype distributionc | PHWEd | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | |||||||||||
11 | 12 | 22 | 11 | 12 | 22 | Ā | ||||||
ERĪ± | ||||||||||||
āKosior-Jarecka et al. 2019 [30] | Poland | rs12154178 | NTG | 100/43 | 74/NA | 77 | 57 | 6 | 90 | 68 | 6 | 0.111733 |
āKosior-Jarecka et al. 2019 | Poland | HTG | 63/29 | 77.5/NA | 50 | 36 | 7 | 90 | 68 | 6 | 0.111733 | |
āKosior-Jarecka et al. 2019 | Poland | rs1884054 | NTG | 100/43 | 74/NA | 61 | 57 | 17 | 79 | 67 | 19 | 0.410095 |
āKosior-Jarecka et al. 2019 | Poland | HTG | 63/29 | 77.5/NA | 46 | 36 | 6 | 79 | 67 | 19 | 0.410095 | |
ERĪ² | ||||||||||||
āKosior-Jarecka et al. 2019 | Poland | rs1268656 | NTG | 100/43 | 74/NA | 88 | 36 | 8 | 124 | 33 | 5 | 0.142854 |
āKosior-Jarecka et al. 2019 | Poland | HTG | 63/29 | 77.5NA | 66 | 17 | 5 | 124 | 33 | 5 | 0.142854 | |
āKosior-Jarecka et al. 2019 | Poland | rs7159462 | NTG | 100/43 | 74/NA | 102 | 25 | 5 | 142 | 22 | 1 | 0.883193 |
āKosior-Jarecka et al. 2019 | Poland | HTG | 63/29 | 77.5/NA | 75 | 13 | 1 | 142 | 22 | 1 | 0.883193 | |
āMabuchi et al. 2010 [31] | Japan | rs1256031 | NTG | 326/290 | 63.75/65.45 | 59 | 107 | 47 | 49 | 84 | 58 | 0.101595 |
āMabuchi et al. 2010 | Japan | HTG | 326/290 | 63.35/65.45 | 53 | 113 | 46 | 49 | 84 | 58 | 0.101595 | |
āMabuchi et al. 2010 | Japan | rs4986938 | NTG | 326/290 | 63.75/65.45 | 161 | 49 | 3 | 136 | 48 | 7 | 0.294793 |
āMabuchi et al. 2010 | Japan | HTG | 326/290 | 63.35/65.45 | 167 | 40 | 5 | 136 | 48 | 7 | 0.294793 | |