Beni-Suef University Journal of Basic and Applied Sciences

Table 3 The effect of E. rigida methanol extract on the viability of Hep3B and HepG2 cells

From: Evaluation of the antioxidant and cytotoxic potency of Euphorbia rigida and Arbutus andrachne methanol extracts in human hepatocellular carcinoma cell lines in vitro

Concentrations (µg mL⁻¹)	Cell viability % ± SD
	Hep3B cells			HepG2 cells
	24 h	48 h	72 h	24 h	48 h	72 h
Control	100 ± 0.000	100 ± 0.000	100 ± 0.000	100 ± 0.000	100 ± 0.000	100 ± 0.000
Solvent control (DMSO)	97.32 ± 0.005	97.19 ± 0.024	96.88 ± 0.116	96.30 ± 0.015	96.59 ± 0.042	96.49 ± 0.020
Farmorubicin 40	1.41 ± 0.134*	1.05 ± 0.008*	0 ± 0.000*	1.63 ± 0.015*	0 ± 0.000*	0 ± 0.000*
25	128.40 ± 0.015*	102.51 ± 0.088	97.40 ± 0.004	97.88 ± 0.166	92.98 ± 0.140	84.34 ± 0.142*
50	125.44 ± 0.033*	100.93 ± 0.148	95.30 ± 0.079	94.05 ± 0.073	90.36 ± 0.189	83.76 ± 0.085*
100	123.37 ± 0.098*	99.88 ± 0.088	85.89 ± 0.109	93.20 ± 0.035	83.49 ± 0.384*	80.72 ± 0.184*
150	110.50 ± 0.233	94.95 ± 0.113	81.69 ± 0.065*	89.52 ± 0.031	82.37 ± 0.040*	77.62 ± 0.057*
200	104.10 ± 0.052	94.72 ± 0.038	81.10 ± 0.017*	86.41 ± 0.038	80.58 ± 0.153*	67.11 ± 0.420*
400	101.48 ± 0.056	87.68 ± 0.053	80.63 ± 0.028*	84.00 ± 0.023*	70.12 ± 0.029*	59.11 ± 0.117*
500	99.26 ± 0.018	82.54 ± 0.285*	76.17 ± 0.209*	72.68 ± 0.009*	58.92 ± 0.087*	45.91 ± 0.052*

Data are the mean ± SD of three separate determinations. Means with an asterisk in the same line indicate a significant (p < 0.05) difference between the concentrations tested. Means with asterisks in the same column indicate the significant (p < 0.05) difference between the solvent used

Back to article page