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Table 3 Relation between the concentrations of AgNPs and MIC values of antibiotics among ESBL producing E. coli isolates

From: Combination of silver nanoparticles with ineffective antibiotics against extended spectrum beta-lactamases producing isolates at Alexandria Main University Hospital, Egypt

Antibiotics (MICs)

MIC of silver in combination

Ag/2

Ag/4

Ag/8

Ag/16

No. (%)

No. (%)

No. (%)

No. (%)

Ampicillin

S (≤ 8 µg/ml)

30 (85.71%)

28 (80.00%)

5 (14.29%)

0 (00.00%)

I (= 16 µg/ml)

4 (11.43%)

6 (17.14%)

25 (71.42%)

3 (8.57%)

R (≥ 32 µg/ml)

1 (2.86%)

1 (2.86%)

5 (14.29%)

32 (91.43%)

Cefotaxime

S (≤ 1 µg/ml)

32 (91.43%)

30 (85.71%)

6 (17.14%)

0 (00.00%)

I (= 2 µg/ml)

3 (8.57%)

5 (14.29%)

24 (68.57%)

9 (25.71%)

R (≥ 4 µg/ml)

0 (00.00)

0 (00.00%)

5 (14.29%)

26 (74.29%)

Ceftazidime

S (≤ 4 µg/ml)

31 (88.57%)

30 (85.71%)

4 (11.43%)

0 (0.00%)

I (= 8 µg/ml)

4 (11.43%)

5 (14.29%)

25 (71.43%)

6 (17.14%)

R (≥ 16 µg/ml)

0 (00.00%)

0 (00.00%)

6 (17.14%)

29 (82.86%)

Ciprofloxacin

S (≤ 0.06 µg/ml)

32 (91.43%)

31 (88.57%)

6 (17.14%)

0 (00.00%)

I (0.12–0.5 µg/ml)

3 (8.57%)

4 (11.43%)

26 (74.29%)

8 (22.86%)

R (≥ 1 µg/ml)

0 (00.00%)

0 (0.00%)

3 (8.57%)

27 (77.14%)

  1. S, sensitive; I, intermediate; R, resistant