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Table 3 Relation between the concentrations of AgNPs and MIC values of antibiotics among ESBL producing E. coli isolates

From: Combination of silver nanoparticles with ineffective antibiotics against extended spectrum beta-lactamases producing isolates at Alexandria Main University Hospital, Egypt

Antibiotics (MICs) MIC of silver in combination
Ag/2 Ag/4 Ag/8 Ag/16
No. (%) No. (%) No. (%) No. (%)
Ampicillin
S (≤ 8 µg/ml) 30 (85.71%) 28 (80.00%) 5 (14.29%) 0 (00.00%)
I (= 16 µg/ml) 4 (11.43%) 6 (17.14%) 25 (71.42%) 3 (8.57%)
R (≥ 32 µg/ml) 1 (2.86%) 1 (2.86%) 5 (14.29%) 32 (91.43%)
Cefotaxime
S (≤ 1 µg/ml) 32 (91.43%) 30 (85.71%) 6 (17.14%) 0 (00.00%)
I (= 2 µg/ml) 3 (8.57%) 5 (14.29%) 24 (68.57%) 9 (25.71%)
R (≥ 4 µg/ml) 0 (00.00) 0 (00.00%) 5 (14.29%) 26 (74.29%)
Ceftazidime
S (≤ 4 µg/ml) 31 (88.57%) 30 (85.71%) 4 (11.43%) 0 (0.00%)
I (= 8 µg/ml) 4 (11.43%) 5 (14.29%) 25 (71.43%) 6 (17.14%)
R (≥ 16 µg/ml) 0 (00.00%) 0 (00.00%) 6 (17.14%) 29 (82.86%)
Ciprofloxacin
S (≤ 0.06 µg/ml) 32 (91.43%) 31 (88.57%) 6 (17.14%) 0 (00.00%)
I (0.12–0.5 µg/ml) 3 (8.57%) 4 (11.43%) 26 (74.29%) 8 (22.86%)
R (≥ 1 µg/ml) 0 (00.00%) 0 (0.00%) 3 (8.57%) 27 (77.14%)
  1. S, sensitive; I, intermediate; R, resistant