Skip to main content

Table 2 Effects of NAC as compared to the reference treatment DEXA on AEC and NOx in BALF pellets in asthmatic rats

From: Immunomodulatory and anti-inflammatory effects of N-acetylcysteine in ovalbumin-sensitized rats

Groups

Parameters

AEC (cumm)

NOx (µMol/L)

Normal control

862 ± 74.6

20.9 ± 2.46

Asthma control

7100 ± 643.2a

56 ± 4.5a

DEXA (1 mg/kg; p.o.)

1650 ± 311.5b

33.6 ± 4.52b

NAC (300 mg/kg; p.o.)

2308 ± 381.5b

35 ± 4b

NAC (500 mg/kg; p.o.)

1200 ± 173.6b

22.8 ± 1.87b

  1. Data were expressed as mean ± SEM (N = 8 rats). Statistical analysis was carried out by one-way analysis of variance (ANOVA) followed by Bonferroni test
  2. aSignificantly different from normal control at p < 0.05
  3. bSignificantly different from asthma control group at p < 0.05
  4. cSignificantly different from DEXA group at p < 0.05