Table 4 ADME properties of Cajanus cajan derived compounds that showed inhibitory activity HDACs
S/N | Compounds | Molecular Weight | H-bond acceptor | H-bond donor | MlogP | Rotatable bonds | Lipinski violation |
|---|---|---|---|---|---|---|---|
1 | Betulinic acid | 456.7 | 2 | 3 | 5.82 | 2 | 1 |
2 | Genistin | 432.38 | 10 | 6 | − 1.61 | 4 | 1 |
3 | Orientin | 448.38 | 11 | 8 | − 2.51 | 3 | 2 |
4 | Vitexin | 432.38 | 10 | 7 | − 2.02 | 3 | 1 |