Table 8 Mean plasma concentrations of TGF-β1 according to (+915 G/C) genotypes and IL-6 according to (−174 G/C) genotypes in controls and ovarian cancer patients
Genotype | Control group (N = 48) (Mean ± SE) | Ovarian cancer (N = 48) (Mean ± SE) | P value |
|---|---|---|---|
IL-6 (−174 G/C) (pg/ml) (N) | |||
G/G (34, 23) | 31.03 ± 3.40 | 95.16 ± 4.27 | P < 0.001*** |
G/C (13, 3) | 24.45 ± 4.88 | 34.16 ± 2.20 | NS |
C/C (1, 22) | 5.20 ± 0.0 | 109.31 ± 4.55 | P < 0.001*** |
G (47, 26) | 29.21 ± 2.81 | 88.12. ± 5.42 | P < 0.001*** |
C (14, 25) | 23.07 ± 4.73 | 100.30 ± 6.39 | P < 0.001*** |
TGF-β1 (+915G/C) (Pg/ml) (N) | |||
G/G (41, 31) | 67.34 ± 8.08 | 142.57 ± 6.72 | P < 0.001*** |
G/C (6, 17) | 66.56 ± 15.30 | 133.01 ± 4.13 | P < 0.01** |
C/C (1, 0) | – | – | – |
G (47, 48) | 67.24 ± 7.26 | 139.18 ± 4.59 | P < 0.001*** |
C (7, 17) | 89.11 ± 25.99 | 133.01 ± 4.13 | P < 0.001*** |