Table 3 Different anti-microbial peptides (AMPs) produced by halophiles
From: Biotechnological potentials of halophilic microorganisms and their impact on mankind
Short peptides | Source organism | Mechanism | Applications (in biomedicine) | References |
|---|---|---|---|---|
Cyclic dipeptides (CDPs) | Pseudomonas aeruginosa | Cyclodipeptides (CDPs) are capable of inducing apoptosis | Inhibitory effect towards plant pathogens, and human pathogen | [66] |
Halocin H4 | Haloferax mediterranei | Production of exopolysaccharides (EPS) | Inducer or activator of DNA uptake | [65] |
Microcin E492 | Klebsiella pneumoniae | Induce apoptosis in human cell lines | Bactericidal activity to Enterobacteriaceae | [67] |
Streptomonomicin (STM) | Streptomonospora alba | Mutation of response regulator gene (walR) | Against Bacillus anthracis | [68] |
Nisin | Lactococcus lactis | Positive charged molecule that causes pore development in the cell membrane of the target organism and thereby results in cytoplasmic membrane depolarization | Anticancer agent | [69] |