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Table 6 Univariate and multivariate analysis for the risk factor of colorectal cancer

From: Linking insulin like growth factor-1 (IGF-1) rs6214 gene polymorphism and its serum level with risk of colorectal cancer

 

Univariate

#Multivariate

p

OR (95% CI)

p

OR (95% CI)

Sex (female)

0.524

1.226 (0.656–2.291)

  

Age

0.242

0.984 (0.959–1.011)

  

ALT

0.250

0.962 (0.900–1.028)

  

AST

0.290

1.042 (0.966–1.124)

  

UREA

0.092

0.970 (0.937–1.005)

  

Creatinine

0.554

1.513 (0.385–5.949)

  

CA19-9 (U/ml)

< 0.001*

1.097 (1.051–1.145)

< 0.001*

0.936 (0.904–0.969)

CEA (mg/dl)

0.992

4.031 (0.0–6.511037753104e)

  

Serum IGF-1 (ng/ml)

< 0.001*

1.121 (1.079–1.164)

< 0.001*

1.413 (1.222–1.634)

IGF.rs6214

    

CC®

    

CT

< 0.001*

8.333 (3.391–20.480)

0.103

0.264 (0.053–1.308)

TT

< 0.001*

10.417 (4.425–24.523)

< 0.001*

0.002 (0.0–0.037)

  1. *Statistically significant at p ≤ 0.05