Table 9 Pre-compression parameters
From: Development and characterization of solid dispersion-based orodispersible tablets of cilnidipine
Formulations | Bulk density (g/ml) | Tapped density (g/ml) | Hausner′s ratio | Carr’s index (%) | Angle of repose |
|---|---|---|---|---|---|
F1 | 0.31 ± 0 | 0.32 ± 0 | 1.03 ± 0 | 3.10 ± 0 | 32.95 ± 1.29 |
F2 | 0.31 ± 0.01 | 0.32 ± 0.007 | 1.03 ± 0 | 3.05 ± 0.03 | 33.36 ± 1.54 |
F3 | 0.30 ± 0.01 | 0.32 ± 0 | 1.04 ± 0.01 | 3.03 ± 2.44 | 35.31 ± 0.47 |
F4 | 0.30 ± 0.01 | 0.32 ± 0.007 | 1.05 ± 0.01 | 5.13 ± 1.44 | 33.97 ± 1.46 |
F5 | 0.32 ± 0.007 | 0.34 ± 0.01 | 1.05 ± 0.01 | 4.87 ± 1.30 | 33.16 ± 1.14 |
F6 | 0.31 ± 0.007 | 0.32 ± 0.01 | 1.04 ± 0.01 | 4.06 ± 1.41 | 34.0 ± 1.42 |
F7 | 0.30 ± 0.01 | 0.32 ± 0.007 | 1.05 ± 0.01 | 5.13 ± 1.44 | 34.29 ± 1.25 |
F8 | 0.31 ± 0.007 | 0.33 ± 0 | 1.05 ± 0.01 | 5.05 ± 1.42 | 32.21 ± 0.26 |
F9 | 0.30 ± 0.007 | 0.31 ± 0.01 | 1.04 ± 0.01 | 4.19 ± 1.45 | 34.45 ± 1.8 |
F10 | 0.31 ± 0.01 | 0.32 ± 0.01 | 1.05 ± 0.01 | 5.11 ± 1.47 | 32.24 ± 0.24 |
F11 | 0.31 ± 0.007 | 0.32 ± 0.007 | 1.03 ± 0 | 3.07 ± 0.03 | 33.49 ± 1.72 |
F12 | 0.32 ± 0.007 | 0.33 ± 0 | 1.03 ± 0 | 3.0 ± 0.04 | 32.13 ± 0.30 |