Fig.8From: Alpha-lipoic acid-role in improving both reserpine toxicity and paroxetine treatment in the cerebral cortex of albino rats; histological, ultrastructural, immunohistohemical and biochemical studiesElectron micrographs of the cerebral cortex obtained from the reserpine-treated rats showing a: degenerated pyramidal cell (P) with rarified cytoplasm (*) and a granular neuron with shrunk nucleus (N) and severe clumping chromatin (arrow), b: showing apoptotic granular cells (G) had shrunk nuclei (N), apoptotic blebs (arrow), the cytoplasm contained numerous degenerative vacuoles (V), and mitochondria (M). c: showing degenerated nerve axons (thin arrow), with splitting or discontinuity of myelin sheath (thick arrow), rarified axoplasm (*), and dense mitochondria (M)Back to article page