Fig. 3
From: Assessment of nano-iron particles impact on the reproductive health of female Wistar rats
Photomicrographs of an ovarian section (H&E stain, n = 3 from each group). Control (A): normal atretic follicle (AF), Graafian follicle (GF), stroma (S), corpus luteum (CL), and secondary follicles (SF). Low dose (B–D): degenerative follicles, the primary follicle (white arrow), the tertiary follicle (red arrow), degenerated secondary follicle (black arrow), vacuolation (blue arrow), cyst (curved blue arrow), corpus luteum (thin arrow), dilated vessels in the ovarian medulla and hemorrhage (yellow arrow), and atretic follicle (orange arrow), apoptotic cells having deep acidophilic cytoplasm with pyknotic nuclei (green arrow), and abnormal spaces within the stroma (vacuolation) (blue arrow). D Degenerated granulosa cells (blue arrows), pyknosis (green arrow), and a slight degeneration in ovarian stromal cells or theca (blue arrow). High dose (E–I): degenerated corpus luteum (thin black arrow), the primary follicle (white arrow), the atretic follicle (orange arrow), follicular cysts (bent blue arrow), congested blood vessels (yellow arrow), and vacuolation in stromal cells (blue arrow), degenerated granulosa cells (black arrow), apoptotic cells having deep acidophilic cytoplasm with pyknotic nuclei (green arrow)