Skip to main content

Table 1 Series of synthesized flavonoids from IOS

From: Flavonoids as dual inhibitors of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): molecular docking and in vitro studies

Class of flavonoids

Compounds

R1

R2

R3

R4

Molecular formula

NC1

H

H

OCH3

OCH3

C17H16O4

NC6

OCH3

H

OCH3

OCH3

C18H18O5

NC7

CH2CH3

H

OCH3

OCH3

C19H20O4

NC5

CH2CH3CH3

H

OCH3

OCH3

C20H22O4

NC2

Br

H

OCH3

OCH3

C17H15O4Br

NC8

H

NO2

OCH3

OCH3

C17H15NO6

NF2

H

H

OCH3

OCH3

C17H16O4

NF4

CH2CH3

H

OCH3

OCH3

C19H20O4

NF5

CH2CH3CH3

H

OCH3

OCH3

C20H22O4

NF7

H

NO2

OCH3

OCH3

C17H15NO6

NPC3 (Pinostrobin)

H

H

  

C16H14O4

NPC5

OCH3

H

C17H16O5

NPC7

CH2CH3

H

C18H18O4

NPC6

CH2CH3CH3

H

C19H20O4

NPC4

Br

H

C16H13O4Br

NPC8

H

NO2

C16H13NO6

NP4 (Pinocembrin)

H

H

C15H12O4

NP5

OCH3

H

C16H14O5

NP6

CH2CH3CH3

H

C18H18O4

NP9

CH2CH3

H

C17H16O4

NP7

Br

H

C15H11O4Br