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Table 1 Comparison of different types of LFIA tests developed for COVID-19 detection

From: Screening and confirmation tests for SARS-CoV-2: benefits and drawbacks

Types of LFIA

No. of positive patient samplesa

No. of negative patient samplesb

No. of other samplesc

Sample type

Sensitivity (%)

Specificity

(%)

Reference

NG-Test IgG-IgM LFIA

82

57

25

Human serum

100%

(98%) compared to ELISA (95.8%)

[52]

Lanthanide-doped polystyrene nanoparticles (LNP) LFIA

7

12

ND

Human serum

ND

ND

[66]

Surface – enhanced Raman scattering-based LFIA (SERS-LFIA)

19

49

ND

Human serum

100%

100%

[67]

QB-based LFIA

69

53

ND

Human serum

97.1%

100%

[68]

UK-RTC Abc-19 Rapid Test LFIA

304

350

ND

Human serum

97.70%

100%

[69]

  1. LFIA lateral flow immunoassay, ND not done, RT-PCR reverse transcription polymerase chain reaction
  2. aSARS-CoV-2 RT-PCR results are positive
  3. bHealthy controls
  4. cBanked samples from patients with additional viral illnesses, including SARS-CoV-2