Fig. 6

A photomicrograph of PCNA immunohistochemically stained left hippocampus sections. Positive PCNA nuclear immunoreactions in glial cells (arrow heads) and cells of the SGZ (dashed arrow): [a–c control group, d–f hypothyroidism group, g–i recovery group and j–l thyroxine-treated group]: Nerve cells of PL in CA1 (a, d, g, j) and CA3 (b, e, h, k) regions show negative immunoreactivity. c, f, i, l SL of DG shows positive immunoreactivity in the nuclei of some cells of SGZ in control (c), in few cells in groups II (f) and III (i), and in numerous cells in group IV (l). Immunopositive reactions are also seen in the nuclei of some glial cells. [Immunohistochemical stain for PCNA, × 400]. m Histogram showing the mean number of PCNA immunopositive nerve cells in SGZ of DG: significant compared to group I (*), group II (#), and group III ($), [significant difference at P < 0.05]