Fig. 8
A photomicrograph of synaptophysin immunohistochemically stained sections in the left hippocampus. Positive synaptophysin immunoreactivity in the cytoplasm of neurons (wavy arrows) of PL, ML, and OL in CA1 & CA3 and in DOL, DML, and GL of DG: [a–c control group, d–f hypothyroidism group, g–i recovery group and j–l thyroxine-treated group]: a, j CA1, b, k CA3 and c, l SL of DG showing widespread dense positive immunoreactivity. d, g CA1, e, h CA3 and f, i SL of DG showing scattered light positive immunoreaction. [Immunohistochemical stain for synaptophysin, × 400]. m Histogram showing values of mean area percent of synaptophysin immunopositive reaction in CA1, CA3 & DG. And n Mean values of optical density of synaptophysin immunopositive reaction in the same areas: significant compared to group I (*), group II (#), and group III ($), (significant difference at P < 0.05)