Fig. 1

ERCC genetic alterations: ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8 analyses using cBioportal. A Summary of ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8 gene alterations in breast cancer studies in cBioportal. B Oncoprint ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8 gene analyses using samples from the 2021 provisional study of The Metastatic Breast Cancer Project. C Copy number alterations (CNAs) in ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8 genes using samples from the 2021 provisional study of The Metastatic Breast Cancer Project. Statistical analyses were performed using One-Way Analysis of Variance with Tukey’s multiple comparison tests. * indicates p < 0.05. D Mutations in ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8 genes in samples from the 2021 provisional study of The Metastatic Breast Cancer Project. Pathway enrichment analyses of ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8 gene alterations using (E). Pathway Mapper and (F). NDEx data