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Table 3 Effect of crude extract, methanol, n-hexane fractions of V.C leaves and metformin Hematological parameters in different experimental groups

From: Evaluation of the therapeutic potentials of extract fractions of Vernonia calvoana on streptozotocin-induced diabetic rats: approach through in silico, in vitro and in vivo studies

Grouping

PLT

WBC (X103/µl)

RBC (X103/µl)

HGB (g/dl)

HCT (%)

MCV (fl)

MCHC (dl)

MCH (Pg)

NC

12.03 ± 1.03

7.97 ± 0.57

14.40 ± 0.55

47.93 ± 1.57

60.78 ± 4.78

30.13 ± 1.56

18.16 ± 0.63

712 ± 56.58

DC

17.63 ± 1.92*

8.05 ± 0.25

14.66 ± 0.27

48.13 ± 1.58

59.76 ± 0.40

30.50 ± 0.45

18.26 ± 0.24

737 ± 99.34

MET

15.16 ± 2.16*a

7.73 ± 0.21

14.93 ± 0.54

47.53 ± 1.33

61.43 ± 03.17

31.49 ± 0.51

19.36 ± 0.41

744 ± 75.80

VC crude

18.32 ± 9.46*

7.93 ± 0.98

14.13 ± 1.27

43.76 ± 4.77*a

55.63 ± 1.22*

32.43 ± 0.79*a

18.12 ± 0.83

426 ± 87.12*a.b

VC meth

10.91 ± 0.15a

7.53 ± 0.31

14.18 ± 0.50

43.53 ± 2.06*a

57.73 ± 1.32*

32.43 ± 0.43*a

18.73 ± 0.40

893 ± 38.49*a.b

VC nhexane

12.13 ± 1.48a

7.25 ± 0.39

13.06 ± 0.34

40.06 ± 2.33*a

55.30 ± 0.79*

32.73 ± 1.05*a

18.06 ± 0.61

822.33 ± 40.35*a,b

  1. Values are Mean ± SEM. NC, Normal control; DC: Diabetic control; MET: Metformin, V.C crude; Vernonia calvoana crude, VC meth: Vernonia calvoana methanol and VC n-hexane: Vernonia calvoana n hexane. Data are represented as mean ± SEM. *p < 0.05 versus NC and ap < 0.05 versus DC. n = 6