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Beni-Suef University Journal of Basic and Applied Sciences
Fig.3 | Beni-Suef University Journal of Basic and Applied Sciences

Fig.3

From: The alleviative efficacy of sildenafil and chrysin against zinc oxide nanoparticles-provoked hepatic and blood toxicity: role of MyD88/NF-κB1/TNF-α pathway

Fig.3

Effect of chrysin and sildenafil on hepatic histopathological sections. Photomicrograph of H&E-stained sections from the liver showing normal histological configurations of hepatic cords (arrows), portal triads (curved arrows), Kupffer cells (thick arrows) and central veins (arrowhead) in control group (A, B), sildenafil group (C, D) and chrysin group (E, F). Congestion of central vein (arrowhead) and sinusoids (thick arrow), cytoplasmic vacuolation of most hepatic parenchyma (curved arrow). As well, inflammatory cells aggregate within some portal triads (arrow) in ZnO-NPs group (G, H). Centro lobular fatty degenerations of hepatocytes (arrow) in prophylaxis chrysin group (I). Unicellular hepatic necrosis (arrow) and mildly congested sinusoids (thick arrow) in the chrysin-treated group (J). Apparently, Normal hepatic parenchyma with minute interstitial round cells infiltrates (arrows) in the sildenafil-treated group (K) and the combined-treated group (L) (H&E, ×400, scale bar 20 μm)

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