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Beni-Suef University Journal of Basic and Applied Sciences
Fig. 4 | Beni-Suef University Journal of Basic and Applied Sciences

Fig. 4

From: The alleviative efficacy of sildenafil and chrysin against zinc oxide nanoparticles-provoked hepatic and blood toxicity: role of MyD88/NF-κB1/TNF-α pathway

Fig. 4

Effect of chrysin and sildenafil on hepatic immunohistochemical sections. Photomicrograph of immunostained sections of the liver for caspase-3 showed nearly undetectable stained hepatic cells in the control group (A), the sildenafil group (B), the chrysin group (C), and the combined-treated group (H). However, high expression of positive cells (arrow) was demonstrated in the Zinc oxide nanoparticles group (D). A moderate number of immune labeled cells (arrow) were seen in both the chrysin prophylaxis (E) and the chrysin-treated (F) groups. Low expression of positive cells (arrow) for caspase-3 was seen in the sildenafil-treated group (G) (Caspase 3 immunostaining, × 400, scale bar 20 μm)

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