Table 2 Effect of Chrysin and sildenafil against ZnO-NPs triggered hepatocytes DNA damage
N = 6 | Control | ZnO-NPs | Sildenafil | Chrysin | Prophylaxis Chrysin | Chrysin-treated | Sildenafil-treated | Combined-treated |
|---|---|---|---|---|---|---|---|---|
Untailed (%) | 97.00 ± 0.36 A | 83.50 ± 0.22 B | 97.33 ± 0.33A | 97.00 ± 0.36A | 97.17 ± 0.40 A | 87.17 ± 0.3 C | 89.33 ± 0.21 D | 93.67 ± 0.61 E |
Tailed (%) | 3.667 ± 0.33 A | 17.67 ± 0.49 B | 3.667 ± 0.33 A | 4.000 ± 0.36 A | 13.33 ± 0.21 C | 11.83 ± 0.30 CD | 10.83 ± 0.30 D | 8.000 ± 0.363 E |
Tail length (µm) | 1.312 ± 0.0047 A | 4.283 ± 0.007 B | 1.337 ± 0.007 A | 1.342 ± 0.006 A | 3.877 ± 0.006 C | 3.828 ± 0.008 D | 3.673 ± 0.003 E | 2.967 ± 0.01 F |
Tail DNA (%) | 1.492 ± 0.004 A | 3.987 ± 0.005 B | 1.483 ± 0.004 A | 1.488 ± 0.004 A | 3.715 ± 0.004 C | 3.667 ± 0.004 D | 3.390 ± 0.003 E | 2.965 ± 0.004 F |
Tail moment (Unit) | 1.955 ± 0.004 A | 16.90 ± 0.006 B | 1.953 ± 0.006 A | 1.957 ± 0.004 A | 14.18 ± 0.008 C | 14.05 ± 0.01 D | 12.47 ± 0.006 D | 10.33 ± 0.01 E |