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Beni-Suef University Journal of Basic and Applied Sciences

Table 4 Effect of Chrysin and sildenafil against ZnO-NPs induced hematological toxicity

From: The alleviative efficacy of sildenafil and chrysin against zinc oxide nanoparticles-provoked hepatic and blood toxicity: role of MyD88/NF-κB1/TNF-α pathway

N = 6

Control

ZnO-NPs

Sildenafil

Chrysin

Prophylaxis Chrysin

Chrysin-treated

Sildenafil-treated

Combined-treated

WBCs (*103) U/L

13.77 ± 0.79

A

21.58 ± 0.69

B

16.95 ± 0.83

A

17.21 ± 0.92

A

19.45 ± 0.37

B

19.16 ± 0.51

B

18.88 ± 0.52

B

17.00 ± 0.53

C

RBCs

(*106)

U/L

0.673 ± 0.009

A

0.290 ± 0.01

B

0.670 ± 0.01

A

0.675 ± 0.008

A

0.386 ± 0.01

C

0.381 ± 0.01

C

0.476 ± 0.01

D

0.503 ± 0.01

D

Platelets

(*103) U/L

1784 ± 10.62 A

1119 ± 12.57 B

1826 ± 15.7 A

1791 ± 4.73

A

1533 ± 16.7

C

1580 ± 10.07

C

1650 ± 15.29 D

1759 ± 11.18

A

  1. WBCs white blood cells, RBCs red blood cells
  2. Values represent Mean ± SEM. Within the same row, values without common subscript capital letters are significantly different (p < 0.0001)
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