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Beni-Suef University Journal of Basic and Applied Sciences
Fig. 1 | Beni-Suef University Journal of Basic and Applied Sciences

Fig. 1

From: Polydatin nanoparticles attenuate oxidative stress and histopathological changes in streptozotocin model of diabetic nephropathy: targeting Nrf2/HO-1/NF-κβ signaling pathways

Fig. 1

a–d Body weight changes (g) between (initial body weight and final body weight), kidney weight (g), FBS prior treatment and FBS after treatment (mg/dl) and HbA1c (%) of normal control animals (C), diabetic control group (D), diabetic animals treated with blank chitosan nanoparticles (D + CSNPs), diabetic group treated with polydatin-loaded chitosan nanoparticles (D + POLY-CSNPs), polydatin (D + POLY), and metformin HCl (D + METF), respectively, for 4 weeks. Data are expressed as mean ± SEM (n = 6). ###P < 0.001 versus control; *P < 0.05; **P < 0.01 and ***P < 0.001 versus diabetic control

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