Table 3 Droplet characteristics of the various LSES

Batch

A1:0.5

B1:0.5

A3:1

B3:1

C3:1

Droplet size (nm)

39.88 ± 4.0

14.96 ± 6.0

14.42 ± 2.5

12.10 ± 1.7

8.95 ± 0.9

Polydispersity index

0.25 ± 0.04

0.12 ± 0.009

0.09 ± 0.002

0.11 ± 0.03

0.09 ± 0.005

Kolliphor HS 15 Lumefantrine LSES

32:49:19

30:47:23

24:57:19

Droplet size (µm)

1589 ± 104

1579 ± 200

2022 ± 311

Polydispersity index

0.33 ± 0.068

0.34 ± 0.099

0.27 ± 0.04

Kolliphor EL Lumefantrine LSES

34:50:16

34:55:11

34:60:06

34:65:01

Droplet size (nm)

8493 ± 778

4229 ± 709

8852 ± 1395

341.95 ± 20.6

Polydispersity index

0.64 ± 0.04

0.8 ± 0.05

0.611 ± 0.2

0.48 ± 0.02

Lumefantrine + Kollidone VA64 fine LSES

50

55

60

65

Droplet size

3897 ± 1235

2228.5 ± 419

402.6 ± 85

504.6 ± 4.5

Polydispersity index

0.9 ± 0.2

0.9 ± 0.12

0.9 ± 0.008

0.7 ± 0.008