Table 3 Calculated and predicted antitubercular activity by model equation and LOO
S.No. | Code | Exp. endpoint | Pred. by model eq | Pred.Mod. Eq Res | Pred. LOO | Pred. LOO Res |
|---|---|---|---|---|---|---|
1. | THN-1 | 6.1549 | 6.1091 |  − 0.0458 | 6.1043 |  − 0.0506 |
2. | THN-2 | 6.0458 | 6.1333 | 0.0875 | 6.1447 | 0.099 |
3. | THN-3 | 5.7212 | 5.6667 |  − 0.0545 | – | – |
4. | THN-4 | 5.4089 | 5.8036 | 0.3947 | – | – |
5. | THN-5 | 5.8125 | 5.9075 | 0.095 | 5.9224 | 0.1099 |
6. | THN-6 | 6.0269 | 5.7034 |  − 0.3234 | 5.6733 |  − 0.3536 |
7. | THN-7 | 5.7212 | 5.7354 | 0.0142 | 5.7368 | 0.0156 |
8. | THN-8 | 6.0044 | 5.8261 |  − 0.1783 | – | – |
9. | THN-9 | 5.8416 | 5.7658 |  − 0.0758 | 5.7525 |  − 0.0892 |
10. | THN-10 | 5.4437 | 5.4471 | 0.0034 | 5.4476 | 0.0039 |
11. | THN-11 | 5.71 | 5.9024 | 0.1925 | 5.9369 | 0.2269 |
12. | THN-12 | 5.1367 | 5.4535 | 0.3168 | 5.4915 | 0.3549 |
13. | THN-13 | Excluded | ||||
14. | THN-14 | Excluded | ||||
15. | THN-15 | 5.5467 | 5.2989 |  − 0.2478 | 5.2456 |  − 0.3011 |
16. | THN-16 | 5.719 | 5.6229 |  − 0.0961 | 5.6048 |  − 0.1141 |
17. | THN-17 | 5.6615 | 5.6545 |  − 0.007 | – | – |
18. | THN-18 | 6.0706 | 6.1091 | 0.0385 | – | – |
19. | THN-19 | 5.9066 | 5.9071 | 0.0005 | 5.9071 | 0.0005 |
20. | THN-20 | 5.7645 | 5.8604 | 0.0959 | 5.8697 | 0.1052 |
21. | THN-21 | 5.7077 | 5.8602 | 0.1525 | 5.8936 | 0.1858 |
22. | THN-22 | 5.7595 | 5.8026 | 0.0431 | 5.8074 | 0.048 |
23. | THN-23 | 6.3188 | 6.2812 |  − 0.0376 | 6.2735 | –0.0453 |
24. | THN-24 | 6.1487 | 6.261 | 0.1122 | 6.2772 | 0.1285 |
25. | THN-25 | 5.4237 | 5.6746 | 0.2509 | – | – |
26. | THN-26 | 6.3372 | 6.2 |  − 0.1373 | 6.184 |  − 0.1532 |
27. | THN-27 | 6.6778 | 6.2596 |  − 0.4181 | 6.1984 |  − 0.4793 |
28. | THN-28 | 6.0223 | 5.6841 |  − 0.3381 | 5.6523 |  − 0.37 |
29. | THN-29 | 5.1427 | 5.5862 | 0.4435 | 5.6363 | 0.4937 |
30. | THN-30 | 5.4191 | 5.4753 | 0.0562 | 5.4827 | 0.0637 |
31. | THN-31 | 5.4078 | 5.4436 | 0.0358 | – | – |
32. | THN-32 | 5.1308 | 5.2398 | 0.1091 | 5.2512 | 0.1205 |
33. | THN-33 | 5.1367 | 5.2107 | 0.0741 | – | – |
34. | THN-34 | 5.4214 | 5.307 |  − 0.1143 | 5.2851 |  − 0.1363 |
35. | THN-35 | 5.1487 | 5.2162 | 0.0675 | 5.2229 | 0.0741 |
36. | THN-36 | 5.1549 | 5.3746 | 0.2197 | 5.4158 | 0.2609 |
37. | THN-37 | 5.1367 | 5.1372 | 0.0005 | 5.1373 | 0.0006 |
38. | THN-38 | 5.0809 | 4.9796 |  − 0.1013 | 4.9621 |  − 0.1188 |
39. | THN-39 | 5.4547 | 5.4032 |  − 0.0515 | 5.3887 |  − 0.066 |
40. | THN-40 | 4.8539 | 4.7545 |  − 0.0994 | 4.7286 |  − 0.1253 |
41. | THN-41 | 5.4584 | 5.5108 | 0.0524 | – | – |
42. | THN-42 | 4.8697 | 4.6874 |  − 0.1822 | – | – |
43. | THN-43 | 5.7167 | 5.7594 | 0.0427 | 5.7695 | 0.0528 |
44. | THN-44 | 5.7352 | 5.4611 |  − 0.2741 | 5.3474 |  − 0.3877 |
45. | THN-46 | 5.433 | 5.4085 |  − 0.0245 | 5.4036 |  − 0.0294 |
46. | THN-47 | 5.4283 | 5.1707 |  − 0.2576 | – | – |
47. | THN-48 | 6.1024 | 6.3042 | 0.2018 | 6.3377 | 0.2354 |
48. | THN-49 | 6.0177 | 5.8456 |  − 0.1721 | – | – |
49. | THN-50 | 6 | 5.8997 |  − 0.1003 | 5.8275 |  − 0.1725 |
50. | THN-51 | 6 | 6.2941 | 0.2941 | – | – |
51. | THN-52 | 6.2147 | 6.2198 | 0.0051 | 6.2203 | 0.0057 |
52. | THN-53 | 5.1805 | 5.313 | 0.1325 | 5.3649 | 0.1844 |
53. | THN-54 | 5.4202 | 5.3236 |  − 0.0967 | 5.3057 |  − 0.1145 |
54. | THN-55 | 5.1805 | 5.3702 | 0.1898 | 5.4581 | 0.2776 |
55. | THN-56 | Excluded | ||||