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Fig. 1 | Beni-Suef University Journal of Basic and Applied Sciences

Fig. 1

From: Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations

Fig. 1

H&E-stained rat cerebral brain slices photomicrographed: 1. In a controlled rat brain, the cerebral meninges have a typical histological anatomy (arrow). 2. In a controlled rat brain, the hippocampus has a typical histological structure (arrow). 3. Neurofibrillary tangles (NFT) are present together with neuronal degeneration in the Alzheimer's disease-induced rat brain (arrow). 4. Rat brain deterioration brought on by Alzheimer's disease with lessened granular layer density. 5. Few Purkinje cells in the cerebellum in the AD rat brain treated with SLSE are displaying signs of degradation. 6. A loss of certain neurons in the cerebral cortex is highlighted in the AD rat brain treated with SLSE (arrows). 7. SLSE-treated AD rat brain with damaged hippocampus neurons (arrows). 8. Meningeal bleeding in an Alzheimer's disease-affected rat brain after treatment with donepezil (arrow)

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