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Table 6 Effect of SLSE on the levels of dopamine, norepinephrine, and serotonin in Alzheimer's -affected rats

From: Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations

 

Norepinephrine (μg/g tissue)

Dopamine (μg/g tissue)

Serotonin (5-HT) (μg/g tissue)

Control

2.0 ± 0.10a

3.2 ± 0.20a

2.9 ± 0.20a

AlCl3-AD

% change

16.4 ± 0.90b

 + 723.0

1.0 ± 0.10b

-68.9

1.0 ± 0.10b

-65.6

Crude extract

% improvement

7.5 ± 0.50a

448.0

2.1 ± 0.20c

34.4

2.1 ± 0.20c

36.6

Donepezil drug

% improvement

5.30 ± 0.50c

558.0

2.7 ± 0.50c

55.2

2.6 ± 0.10c

54.8

  1. Data are presented as mean ± SD (n = 10). The groups that share an identical letter do not differ considerably. Conversely, those that have various letters are, at p ≤ 0.05. The \(\% {\text{change}} = \frac{{{\text{mean}}\;{\text{ of}}\;{\text{ negative }}\;{\text{control}} - {\text{mean }}\;{\text{of }}\;{\text{treatment}}\;{\text{ group}}}}{{{\text{mean }}\;{\text{of }}\;{\text{negative}}\;{\text{ control}}}} \times 100\), \(\% {\text{improvment}} = \frac{{{\text{mean }}\;{\text{of }}\;{\text{positive }}\;{\text{control}} - {\text{mean }}\;{\text{of }}\;{\text{treatment }}\;{\text{group}}}}{{{\text{mean}}\;{\text{of}}\;{\text{ negative }}\;{\text{control}}}} \times 100\)