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Table 9 Histopathological changes in the brain of all treated groups scored

From: Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations

Lesions

G1 control

G2 AD

G3 crude extract

G4 drug

Neuronal degeneration with NFT

0

3

2

1

Congestion of meningeal blood vessels

0

2

0

0

Meningeal haemorrhage

0

2

1

1

Degeneration of hippocampus neurons

0

3

2

1

Degeneration of Purkinje cells in cerebellum

0

2

1

0

Decreased granular layer density in cerebellum

0

2

1

0