Fig. 5From: Phenolic-rich fraction of green tea attenuates histamine-mediated cardiopulmonary toxicity by inhibiting Cox-2/NF-κB signaling pathway and regulating oxidant/antioxidant balancePhotomicrograph demonstrating the pulmonary expression of both Cox-2 and TNF-α immune markers as well as caspase-3 immunostaining in the heart sections of various groups. a–c Control group exhibited negative expression of the above-mentioned immune markers. d–f Group receiving HIS showed strong immunopositivity of Cox-2 and TNF-α in the pulmonary tissue along with strong caspase-3 protein expression in the myocardium. g–i Group receiving HIS + 100 mg PRFGT displayed moderate immunopositivity of Cox-2 and TNF-α in the pulmonary tissue along with negative caspase-3 protein expression in the myocardium. j–l Group receiving HIS + 200 mg PRFGT displayed negative expression of the studied immune markers in both lung and heart sectionBack to article page