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Fig. 5 | Beni-Suef University Journal of Basic and Applied Sciences

Fig. 5

From: Phenolic-rich fraction of green tea attenuates histamine-mediated cardiopulmonary toxicity by inhibiting Cox-2/NF-κB signaling pathway and regulating oxidant/antioxidant balance

Fig. 5

Photomicrograph demonstrating the pulmonary expression of both Cox-2 and TNF-α immune markers as well as caspase-3 immunostaining in the heart sections of various groups. ac Control group exhibited negative expression of the above-mentioned immune markers. df Group receiving HIS showed strong immunopositivity of Cox-2 and TNF-α in the pulmonary tissue along with strong caspase-3 protein expression in the myocardium. gi Group receiving HIS + 100 mg PRFGT displayed moderate immunopositivity of Cox-2 and TNF-α in the pulmonary tissue along with negative caspase-3 protein expression in the myocardium. jl Group receiving HIS + 200 mg PRFGT displayed negative expression of the studied immune markers in both lung and heart section

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