Fig. 13

Electron micrograph of the neuron myelination (myelin sheath) a Control group showing a normal myelin sheath which is thick, electron-dense, and tightly wrapped around axonal cytoplasmic membranes. The myelinated axons had a smooth, regular contour. b Acrolein-treated group showing myelin sheath degeneration, localised disruption of another myelin sheath, and axoplasm vacuolation. c Quercetin nanoparticle-treated group exhibited a typical myelin sheath. d Ameliorative group showing preservation of the myelin sheath, except for a few axons. e Protective group showing great preservation of the myelin sheath, except for very few axons. f Recovery group showing myelin sheath degradation, axoplasm vacuolation, and localised rupture of another myelin sheath. (M, myelin sheath; X, axoplasm; V, vacuole; arrows, focal interruption of myelin sheath). X 20000