Fig. 6

Photomicrograph in CA2 of the hippocampus a Control group showing a normal structure of CA2 with normal pyramidal neurones (arrowheads). b Acrolein-treated group showing a significantly decreased thickness of the Sp layer, with a severe degree of atrophic ischaemic injury of the neuronal cells of the Sp layer (arrowheads) and increased apoptotic neurones (arrows). c Quercetin nanoparticle-treated group showing normal thickness of the Sp layer with normal neurones (arrows). d Ameliorative group showing a reduction in ischaemic neuronal injury in the neuronal cells of the Sp layer (arrows indicate the atrophic cells) with significantly increased Sp layer thickness. e Protective group showing neuronal cells of the Sp layer experienced a significant reduction in neuronal injury (arrows indicate atrophic cells). f Recovery group showing a very slight decrease in ischaemic neuronal injury of the neuronal cells of the Sp layer (arrows) (Sr: stratum radiatum, So: stratum oriens, Sp: stratum pyramidale). (X400)