Fig. 7

Photomicrograph in CA3 of the hippocampus a Control group showing a normal structure of CA3 with normal pyramidal neurones (arrowheads). b Acrolein-treated group showing a reduction in the thickness of the Sp layer as well as a severe degree of atrophic ischaemic injury of the neuronal cells of the Sp layer associated with marked neuronophagia (arrowheads). c Quercetin nanoparticle-treated group showing normal thickness of the Sp layer and normal large neurones (arrows). d Ameliorative group showing a decrease in ischaemic and lytic changes within the neuronal cells of the Sp layer (arrowheads) with significantly improved Sp layer thickness. e Protective group showing that the neuronal cells of the Sp layer appear normal (arrowhead), as does the thickness of the Sp layer. (Sr: stratum radiatum, So: stratum oriens, Sp: stratum pyramidale). (X400)