Assessment of the protective and ameliorative impact of quercetin nanoparticles against neuronal damage induced in the hippocampus by acrolein

Beni-Suef University Journal of Basic and Applied Sciences

Table 3 Semi-quantitative scoring of neuronal histopathological lesions in the hippocampus in the different treatment groups

Groups	Cellular oedema	Ischaemic injury	Malacia	Gliosis	Extent of lesions
Control group	-	-	-	-	-
Acrolein-treated group	+ + +	+ + + +	+ +	+ + +	+ + +
Quercetin nanoparticle-treated group	-	-	-	-	-
Ameliorative group	+	+ +	-	+	+
Protective group	-	+	-	-	-
Recovery group	+ + +	+ + +	+ +	+ +	+ + +

(-) denotes no detectable lesions; (+) mild lesions; (++) moderate lesions; (+++) severe focal lesions; (++++) severe diffuse lesions