Beni-Suef University Journal of Basic and Applied Sciences

Table 1 The association between p21 expression and clinicopathological characteristics of studied colonic lesions

From: The association of p21, inhibin, and Tob-1 expression with the clinicopathological characteristics of benign and malignant colorectal lesions

Variables	P21 expression
Variables	Positive no. (%)	Negative no. (%)	p-value
Age (in years)	51.43 ± 16.14	54.62 ± 16.45	0.25
Age categories
≤ 50 years (45)	22 (49)	23 (51)	0.41
> 50 years (95)	50 (52.6)	45 (47.4)	0.41
Sex
Female (61)	38 (62.3)	23 (37.7)	0.018
Male (79)	34 (43)	45 (57)	0.018
CRC (30)	12 (40)	18 (60)
Type of cancer
Conventional (21)	10 (47.6)	11 (52.4)	0.19
Mucinous (9)	2 (22.2)	7 (77.8)	0.19
Grade
Low-grade CRC (13)	6 (46.2)	7 (53.8)	0.41
High-grade CRC (17)	6 (35.3)	11 (64.7)	0.41
Adenomas (30)	15 (50)	15 (50)	0.30^*
LGD (14)	11 (78.6)	3 (21.4)	0.005
HGD (16)	4 (25)	12 (75)	0.005
UC (30)	19 (63.3)	11 (36.7)	0.06^*
No dysplasia (23)	16 (63.3)	7 (30.4)	0.20
With dysplasia (7)	3 (43)	4 (57)	0.20
Chronic colitis (30)	16 (53.3)	14 (46.7)	0.22^*
Control (20)	10 (50)	10 (50)	0.34^*
Total = 140	72 (51.4)	68 (48.6)

LGD low-grade dysplasia, HGD high-grade dysplasia, UC ulcerative colitis, CRC Colorectal cancer, no. number of cases, %; percentage
^*p-value compared to CRCs

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