Beni-Suef University Journal of Basic and Applied Sciences

Table 3 The association between Tob-1 expression and clinicopathological characteristics of studied colonic lesions

From: The association of p21, inhibin, and Tob-1 expression with the clinicopathological characteristics of benign and malignant colorectal lesions

Variables	Inhibin expression
Variables	Positive no. (%)	Negative no. (%)	p-value
Age (in years)	56.84 ± 12.19	50.48 ± 18.148	0.024
Age categories
≤ 50 years (45)	12 (26.7)	33 (73.3)	0.026
> 50 years (95)	43 (45.3)	52 (54.7)	0.026
Sex
Female (61)	23 (37.7)	38 (62.3)	0.44
Male (79)	32 (40.5)	47 (59.5)	0.44
CRC (30)	25 (83.3)	5 (16.7)
Type of cancer
Conventional (21)	16 (76.2)	5 (23.8)	0.14
Mucinous (9)	9 (100)	0	0.14
Grade
Low-grade CRC (13)	10 (77)	3 (23)	0.37
High-grade CRC (17)	15 (88.2)	2 (11.8)	0.37
Adenomas (30)	18 (60)	12 (40)	0.04^*
LGD (14)	6 (43)	8 (57)	0.78
HGD (16)	12 (75)	4 (25)	0.78
UC (30)	9 (30)	21 (70)	0.001^*
No dysplasia (23)	4 (17.4)	19 (82.6)	0.01
With dysplasia (7)	5 (71.4)	2 (28.6)	0.01
Chronic colitis (30)	3 (10)	27 (90)	0.001^*
Control (20)	0	20 (100)	0.001^*
Total = 140	55 (39.3%)	85 (60.7)

LGD low-grade dysplasia, HGD high-grade dysplasia, UC ulcerative colitis, CRC Colorectal cancer, no. number of cases, %; percentage
^*p-value compared to CRCs

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