Computer aided design of novel antibiotic drug candidate against multidrug resistant strains of Salmonella typhi from pyridine-substituted coumarins

Beni-Suef University Journal of Basic and Applied Sciences

Table 1 2D structures and Invitro MIC values of the investigated compounds

S/n	MIC (μg/mL)	S/n	MIC (μg/mL)
1	200	2	500
3	250	4	200
5	500	6	200
7	63	8	500
9	100	10	500
11	200	12	250
13	100	14	250
15	500	16	200
17	250	18	50
19	100	20	200
21	200	22	250
23	500	24	100
25	100

S/n	MIC (μg/mL)	S/n	MIC (μg/mL)
1	200	2	500
3	250	4	200
5	500	6	200
7	63	8	500
9	100	10	500
11	200	12	250
13	100	14	250
15	500	16	200
17	250	18	50
19	100	20	200
21	200	22	250
23	500	24	100
25	100

S/n	MIC (μg/mL)	S/n	MIC (μg/mL)
1	200	2	500
3	250	4	200
5	500	6	200
7	63	8	500
9	100	10	500
11	200	12	250
13	100	14	250
15	500	16	200
17	250	18	50
19	100	20	200
21	200	22	250
23	500	24	100
25	100

S/n	MIC (μg/mL)	S/n	MIC (μg/mL)
1	200	2	500
3	250	4	200
5	500	6	200
7	63	8	500
9	100	10	500
11	200	12	250
13	100	14	250
15	500	16	200
17	250	18	50
19	100	20	200
21	200	22	250
23	500	24	100
25	100