Table 3 Analysis of COX regression with single and multiple variables for the factors impacting mortality in the cases group
Univariate | #Multivariate | |||
|---|---|---|---|---|
p | HR (LL – UL 95%C.I) | p | HR (LL – UL 95%C.I) | |
Age (years) | 0.216 | 0.962(0.905–1.023) | ||
Menstrual status (Postmenopausal) | 0.879 | 0.906(0.256–3.211) | ||
Family history | 0.572 | 0.045(0.0–2170.328) | ||
Tumor side (left) | 0.817 | 1.162(0.328–4.117) | ||
Pathological subtype (IDC) | 0.770 | 1.362(0.172–10.749) | ||
Pathological stage (≥ 3) | 0.067 | 6.915(0.876–54.596) | ||
Metastasis Status | 0.006* | 6.711(1.732–25.998) | 0.527 | 1.894(0.262–13.699) |
Grade (III) | 0.175 | 2.923(0.620–13.780) | ||
PT status (≥ 3) | 0.201 | 2.282(0.644–8.088) | ||
PN status (≥ 3) | 0.342 | 1.927(0.498–7.453) | ||
ER | 0.207 | 0.443(0.125–1.570) | ||
PR | 0.280 | 0.498(0.140–1.765) | ||
HER2/neu | 0.935 | 0.938(0.199–4.417) | ||
Ki 67 | 0.884 | 0.891(0.189–4.195) | ||
Molecular subtype (Triple negative) | 0.066 | 0.305(0.086–1.083) | ||
CEA value | 0.698 | 1.003(0.986–1.021) | ||
CA15.3.value | 0.002* | 1.010(1.003–1.016) | 0.190 | 1.005(0.998–1.012) |
Chemotherapy status | 0.309 | 29.137(0.044–19,423 | ||
Chemo toxicity | 0.042* | 4.060(1.049–15.707) | 0.782 | 0.751(0.098–5.734) |
Toxicity grade | 0.133 | 2.638(0.744–9.352) | ||
Hormonal ttt | 0.078 | 0.296(0.077–1.146) | ||
Biological treatment | 0.483 | 1.742(0.370–8.204) | ||
miRNA 138 | 0.002* | 0.799(0.694–0.921) | 0.062 | 0.862(0.738–1.008) |
miRNA 127 | 0.020* | 0.841(0.728–0.973) | 0.241 | 0.909(0.776–1.066) |